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Wednesday, July 31, 2013

Inquiry Exercise - Introduction to Bioinformatics

Challenge
  
Diagnose and treat Cancer  by using Bioinformatics 

 It is the year 2014 and in this real world Bioinformatics exercise, you will play the role of a Molecular Pathologist. Your job is to analyze cancer at the genomic (DNA) level and to suggest molecular therapies.  The human genome ( 3 billion nucleotides of DNA sequence) was first sequenced in 2000 and cost about 3 billion dollars. At present, the cost of sequencing the human genome has decreased to $20,000. It is now economical to sequence the genome of human cancer cells to find out what has gone wrong and predict therapies that may work. In this introductory exercise, a preliminary analysis has been performed to identify sequences in a lung tumor that are different from the normal human sequence.  Your job is to determine whether these changes could cause cancer and where possible, suggest molecular therapies.


Click here to download   introductory exercise

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